tag:blogger.com,1999:blog-5506135718533366764.comments2024-03-07T03:43:03.448-05:00RajLabARhttp://www.blogger.com/profile/13811773097412828786noreply@blogger.comBlogger426125tag:blogger.com,1999:blog-5506135718533366764.post-53065591362050301452024-02-05T14:42:30.297-05:002024-02-05T14:42:30.297-05:00More complete and transparent reporting clearly be...More complete and transparent reporting clearly benefits research and the community. Since it has associated cost, each instance is associated with a cost benefit analysis, which can also help determine the degree of documentation. For example, ambiguous and inconclusive results should be reported as having occurred, but their thorough documentation is unlikely to merit the needed time and effort.<br /><br />As you wrote, more complete and transparent disclosure requires a culture change. What can help is the realization of the benefits, including the benefits for the scientific teams engaging in more transparent disclosure of their results. <br /><br /> Nikolai Slavovhttps://nikolai.slavovlab.net/bio/noreply@blogger.comtag:blogger.com,1999:blog-5506135718533366764.post-88040834364090847472021-08-25T15:58:44.647-04:002021-08-25T15:58:44.647-04:00This idea of intellectual dominance reminds me of ...This idea of intellectual dominance reminds me of the lesson 1 of the book "12 rules for life" by Jordan Peterson.Abhinabahttps://www.blogger.com/profile/17561285421232453199noreply@blogger.comtag:blogger.com,1999:blog-5506135718533366764.post-38871417533999415032021-03-30T10:22:45.902-04:002021-03-30T10:22:45.902-04:00Interesting as a person who thinks he has a high m...Interesting as a person who thinks he has a high metabolism (an always have a big breakfast ;)). I think you miss some other potential aspects: a 4th point would be that your food/calorie uptake is less. Your inestines might be less efficient (or the microbes in you inestine) and therefore the calorie uptake is less for the same amount of food compared to another person. Your nody temperature normally don't fluctuate much due to homeostasis. So it implicates that when you produce more heat, your body will try find ways to get rid of the excess of heat by sweating, getting more blood to your skin etc. If the room temperature is lower than your body temperatures there are still possibilities to cool ;) SjonnieDeehttps://www.blogger.com/profile/17260016314572247742noreply@blogger.comtag:blogger.com,1999:blog-5506135718533366764.post-24237256517993093012020-11-19T10:08:34.369-05:002020-11-19T10:08:34.369-05:00I’ve often wondered about heat as a factor. I had ...I’ve often wondered about heat as a factor. I had a pretty bad accident 6 years ago. Head injury. Left me with a permanent migraine. I was unable to exercise and gained 45 pounds. 5 months ago my dr asked me to take phentermine to help lose weight because I was unable to workout as hard as I used to due to the migraine. I lost the 45 pounds in 4 months. It also somehow helped my migraine. So I’ve stayed on a half dose of phentermine since. Here’s the interesting point of all this- my body temp has gone up. I used to be around 96 degrees and now I’m consistently a degree higher. It’s still lower than the normal 98 for most people. But I’m finding that with this 1degree difference I’m maintaining weight much easier. Just thought I’d throw this out there. I know there are other factors involved with phentermine. My blood pressure has always been low (about 107/67). This medication has not increased it. In fact, with the weight loss I’m hovering closer to my pre-accident BP of 98/64. <br />JBkayakinghttps://www.blogger.com/profile/10956571514686852684noreply@blogger.comtag:blogger.com,1999:blog-5506135718533366764.post-34973033575089966072020-11-12T15:23:08.139-05:002020-11-12T15:23:08.139-05:00One thing I never see considered when thinking whe...One thing I never see considered when thinking whether or not some people generate more heat is where the heat is generated. I think we all have encountered people who's extremities seem to always be cold. While internal temperature is similar amongst everyone, how much heat produced in all other areas seems highly variable. A tall skinny person would probably expend much more energy thermo-regulating than a short fat person.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-5506135718533366764.post-69885836072348785322020-09-27T21:43:00.038-04:002020-09-27T21:43:00.038-04:00These days I've been taken by John Carmack'...These days I've been taken by John Carmack's way of talking about ideas https://www.youtube.com/watch?v=dSCBCk4xVa0 . He famously had to try and reject all kinds of things to get Quake to be sufficiently performant. Kent Beck (who introduced him!) summarizes it in https://www.facebook.com/notes/kent-beck/john-carmacks-deep-thoughts-ideas-work-and-emotion/1051813558184841/Gauthamhttps://www.blogger.com/profile/06478500196620910446noreply@blogger.comtag:blogger.com,1999:blog-5506135718533366764.post-89448147068729347742020-07-31T14:17:24.445-04:002020-07-31T14:17:24.445-04:00You describe an optimistic scenario -- and it soun...You describe an optimistic scenario -- and it sounds very nice! I also imagine a more pessimistic scenario when every overlay journal will publish the same "obviously impactful" papers in their field, like all movie theaters screen the same movies. So, I think there is a bit of danger of the rich gets richer phenomenon, which is the opposite of what I would like to see. But I guess there is no reason why both scenarios cannot happen simultaneously, i.e., "blockbuster" overlay journals and "hipster" overlay journals.Sergey Kryazhimskiyhttps://www.blogger.com/profile/11593425680688480257noreply@blogger.comtag:blogger.com,1999:blog-5506135718533366764.post-4311576661571106562020-07-31T12:03:42.577-04:002020-07-31T12:03:42.577-04:00Really nice post. I've been wondering similar ...Really nice post. I've been wondering similar things. But I disagree about your definition of overlay journal. Usually, but not always, the linking *is* formally called publishing. More importantly, usually they do perform peer review just like a typical journal, and one can submit papers to them. This is the big difference between them and someone's Twitter feed or F1000 recommendations.Daniel Weissmanhttp://weissmanlab.github.ionoreply@blogger.comtag:blogger.com,1999:blog-5506135718533366764.post-31167424050528746172020-07-21T01:06:01.361-04:002020-07-21T01:06:01.361-04:00Thanks! That's definitely helpful.Thanks! That's definitely helpful.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-5506135718533366764.post-34761169887682053012020-07-18T22:09:03.865-04:002020-07-18T22:09:03.865-04:00Sure! One thing Nancy Duarte suggests in the book ...Sure! One thing Nancy Duarte suggests in the book is to frequently establish contrasts, with a frequent contrast being the difference between "what is" and "what could be". She summarizes a lot of great presentations and speeches into these sparklines that clearly label the "what is" parts vs. the "what could be" parts.<br /><br />One thing I tried that helped was (1) outline the major "what is" vs. "what could be" parts of my project (2) write each part onto a separate post-it note (3) arrange and re-arrange the post-it notes into a structure that made sense, with frequent switching between "what is" and "what could be". I think it helped establish a rhythm in the presentation. <br /><br />Another concrete thing I did was greatly shorten my introduction to be more like a story with main characters: I personified two cells (giving them names) and showed the different journeys they took, then asked what might be different between the two at the end. It seemed silly to me but the audience really grabbed onto it and ended up staying much more engaged for the rest of the talk. Hope this helps!Eric Sanfordhttps://www.blogger.com/profile/15961577098475463213noreply@blogger.comtag:blogger.com,1999:blog-5506135718533366764.post-75810973517759994942020-07-17T22:41:22.378-04:002020-07-17T22:41:22.378-04:00Thanks for the suggestions. I looked at "Reso...Thanks for the suggestions. I looked at "Resonate" previously, but couldn't see how to apply it to scientific talks (it seemed very heavily geared towards people who do commercial product marketing, etc.).<br /><br />Could you give us some concrete examples of things you changed/did in your presentations as a result of reading the book?<br /><br />Thanks!Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-5506135718533366764.post-76272172015769138652019-08-23T23:13:05.935-04:002019-08-23T23:13:05.935-04:00Thanks Connie. The guide is great. I've used I...Thanks Connie. The guide is great. I've used Illustrator for years, but there are lots of useful features that I didn't know about.A Salty Scientisthttps://www.blogger.com/profile/15267855116935185541noreply@blogger.comtag:blogger.com,1999:blog-5506135718533366764.post-76784485753665545132019-07-04T15:21:25.973-04:002019-07-04T15:21:25.973-04:00This comment has been removed by the author.strongsleepingpillhttps://www.blogger.com/profile/12807437019527928551noreply@blogger.comtag:blogger.com,1999:blog-5506135718533366764.post-709552301933404482019-05-13T15:54:06.654-04:002019-05-13T15:54:06.654-04:00OMG this is why i never read movie reviews for mov...OMG this is why i never read movie reviews for movies i'm excited about beforehand; they always prejudice me toward/against the movie!!!Caroline Bartmanhttps://www.blogger.com/profile/04420722703020468795noreply@blogger.comtag:blogger.com,1999:blog-5506135718533366764.post-77336650322055507972019-05-07T08:06:13.818-04:002019-05-07T08:06:13.818-04:00Interesting post. What I like about open peer rev...Interesting post. What I like about open peer review is that it is useful for teaching other reviewers what they might have missed in their own reviews. (Of course, it could also show them the nasty side of peer review, but I rarely see that in the journals that I have served as Editor for.)<br /><br />Also, I have a slightly different example of this kind of bias. I was asked to review a review paper that was in one of those online discussion journals. Because the authors would figure out who I was, I chose to be not anonymous. I thought the review paper was worthwhile, but there were many flaws in the content and writing that required extensive revisions. If done right, this would probably occupy many months of the authors' time, so I recommended rejection and resubmission after all the flaws were fixed. <br /><br />Friends and colleagues of the coauthors starting posting reviews about how important this paper was to publish, most neglecting my point that it was poorly written and needing substantial work.<br /><br />In this case, the open peer-review process allowed a camp to form around support for the manuscript. I don't know if the Editor took these comments into account in the decision.David Schultzhttps://www.blogger.com/profile/15897825955377060152noreply@blogger.comtag:blogger.com,1999:blog-5506135718533366764.post-21685885884827460092019-04-29T18:54:24.573-04:002019-04-29T18:54:24.573-04:00Hmm. I don't think any of this is particularly...Hmm. I don't think any of this is particularly intrusive, but of course, anyone should feel free to self advocate for what they need or don't need at any time. I think the authors just wanted to provide some ideas for what such self advocation might look like. I think all parties would agree that communication and coming up with a collaborative plan is essential.ARhttps://www.blogger.com/profile/13811773097412828786noreply@blogger.comtag:blogger.com,1999:blog-5506135718533366764.post-77114574652332322802019-04-29T16:49:49.024-04:002019-04-29T16:49:49.024-04:00This is based on the assumption that "trainee...This is based on the assumption that "trainees" (I hate that word)<br />a)want that level of intrusion, and<br />b)are not equipped to self-advocate for what they need Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-5506135718533366764.post-6726658590863728992019-04-29T03:33:36.875-04:002019-04-29T03:33:36.875-04:00Thanks for this sobering article on a difficult to...Thanks for this sobering article on a difficult topic. The same attitude from the PI would probably also be helpful in stressful periods to prevent actually having an episode or simply to not lose motivation. Elias Frimanhttps://www.blogger.com/profile/12723001888300350386noreply@blogger.comtag:blogger.com,1999:blog-5506135718533366764.post-60020180880069034872019-04-16T21:15:14.581-04:002019-04-16T21:15:14.581-04:00To be fair peer reviews are hard to not blog about...To be fair peer reviews are hard to not blog about, especially if your in academia. My friend is a PHD candidate and that is honestly all they talk about. Thank you for giving me a small insight in their world.buy intrusta antivirushttps://steemit.com/instrusta/@foxfire342/instrusta-antivirusnoreply@blogger.comtag:blogger.com,1999:blog-5506135718533366764.post-86857617868482890122019-03-24T05:02:01.195-04:002019-03-24T05:02:01.195-04:00This is one of the most important things that have...This is one of the most important things that have never been said so. Feedback for the speakers is one thing and the structure of the meetings is altogether another level of complexity. Given the vast number of speakers, not to mention grand gala meetings like SfN, how would anyone interested in other topics can learn without getting swamped by data? Is it time that we rethink conference structures?<br /><br />I have to agree that the informal sessions are the best ones. <br /><br />And feedback via QR code is gonna be the thing. I will gladly use it.<br /><br />Thanks.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-5506135718533366764.post-1685575852785157372019-02-04T17:02:36.725-05:002019-02-04T17:02:36.725-05:00I agree with Alejo.I agree with Alejo.Anonymoushttps://www.blogger.com/profile/07869306598191542049noreply@blogger.comtag:blogger.com,1999:blog-5506135718533366764.post-89610265637453045662019-02-04T14:59:54.140-05:002019-02-04T14:59:54.140-05:00I think, like most things in life, it's a prob...I think, like most things in life, it's a problem of incentives. <br />By the time the PIs are invited to give a talk, the incentive assignment is already completed, and there's little left to convince them to work hard enough to do a great job. This is possibly why some of the best talks I hear at meetings come from selected abstracts from students/postdocs/youngest PIs, where the incentives to do well (find a job/position/fellowship) are more immediate, like you suggest. Some PI exceptions to this of course include naturally gifted speakers, etiquette-concerned professors or especially motivated orators. But for the majority out there you still need to have incentives, and preferably immediate ones. As silly as it may sound, I'm willing to suggest that if Keystone announced an award of 2000 USD for the best invited speaker talk it would make even some of the most accomplished mid-level scientists put an extra effort on their preparation. It might sound like a lot, but it's nothing compared to the expenses of the whole conference, and I propose that this would have a qualitative impact. <br /><br />All the best, <br /><br />Alejo<br />(@AlejoFraticelli)Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-5506135718533366764.post-19397416689302322072019-02-04T14:49:50.838-05:002019-02-04T14:49:50.838-05:00I would totally go with the 5-min, or at most 10-m...I would totally go with the 5-min, or at most 10-min format. These talks are bloody hard to prepare, but the effort pays off (and as you say, if the talk is bad, it's over soon anyway). We recently had an introductory session with scientists from a different discipline and campus, with talks 5 min each, and the general feedback from the local colleagues was that they finally understood what each of us were working on - despite having heard each other present in the 30-45 min format multiple times over the last year. <br />The only thing that's important is that people do stick to the allocated time slot. I still can't forget a conference back in 2006 with 10 min slots, where the average de-facto talk duration was three times as long, with all the repercussions to the schedule and the attitude of the participants to each other... <br /><br />Unknownhttps://www.blogger.com/profile/17884702587611862282noreply@blogger.comtag:blogger.com,1999:blog-5506135718533366764.post-9055135685259971312019-02-04T05:05:12.849-05:002019-02-04T05:05:12.849-05:00Great (and brave) post! Thanks for writing down wh...Great (and brave) post! Thanks for writing down what I never dared to say...<br />To me giving a talk is like writing a paper: you get better with practice. This is why some years ago, fed up with the lack of opportunities that we were given, a bunch of PhD students in the University of Barcelona started the "Flash Talks meetings" (https://jipi.cat/en/). There, PhD students from the University and neighbor institutes gather once a year to give very short talks (5') about the research. Time constrains are very very strict and questions are reserved to the end of the sessions. When more than two people want to give a talk on the same topic, the organizers encourage them to meet beforehand and give a slightly longer talk together (this makes them more dynamic and fun, which is great, and also forces them to practice). The audience can vote the best talk, prices are given, there is a lot of feedback from everywhere, and it is an excellent opportunity to practice. And it is fun. PIs are invited to join as an audience, but they are not allowed to give talks: they already practice a lot in their conferences. Oh, and talks are uploaded in the internet, so that you can confront yourself and learn from it. <br />The meeting is a big success, we are already in the 7th edition, which actually takes place today!<br />I think this kind of initiatives where you can already start practicing talking in front of a wide non-intimidating audience should be more common!<br /><br />Cheers and sorry for the long post!!Annahttps://www.blogger.com/profile/17489304014149231880noreply@blogger.comtag:blogger.com,1999:blog-5506135718533366764.post-10644156152492633782019-01-21T09:33:33.665-05:002019-01-21T09:33:33.665-05:00Enzymes can be found all around us. They exist in ...Enzymes can be found all around us. They exist in all forms of lives, including human, plants, bacteria, and other organisms. Any living organism needs enzymes to function properly. <a href="https://www.creative-enzymes.com/resource/Enzymes-Functions_2.html" rel="nofollow">enzymes function</a><br />creative enzymeshttps://www.blogger.com/profile/12088411869536902616noreply@blogger.com